‌Lee Lab

Located at the Chilliwack CEP Campus‌ -  A2105B


Dr Lee specializes in the development and use of aquatic animal cell lines. Her research is funded by NSERC and the current topic of her research is on the Development and use of fish cell lines as integrative tools for research in basic science, ecotoxicology and aquaculture. Her research interests are expanding into the development of cell lines from economically important invertebrates like bees and shellfish. 

Current students in her lab include Sophia Bloch, PhD candiate through Univ. of Waterloo; Sarah Gignac, MSc candidate through UBC; Katelin Spiteri, MSc candidate through WLU; and UFV undergraduates: Andrew Alexander and Marcus Trento; as well as research assistant Fabiola Rojas.

Publications since Dr Lee joined UFV:

  1. Gignac SJ, Vo NTK, Mikhaeil MS, Alexander JAN, MacLatchy DL, Schulte PM, Lee LEJ (2014)Derivation of a continuous myogenic cell culture from an embryo of common killifish, Fundulus heteroclitus. Comparative Biochem Physiol-A (Accepted May 5. DOI 10.1016-Online May 13, 2014)
  2. Vo NTK, Bufalino MR, Hartlen KD, Kitaev V, Lee LEJ (2013) Cytotoxicity evaluation of silica nanoparticles using fish cell lines. In Vitro Cell Dev Biol – Anim (Accepted Nov 29, 2013; IVAN-D-13-00173R1 – Online December 20, 2013)
  3. Vo NTK, Bender AW, Lee LEJ, Lumsden JS, Lorenzen N, Dixon B, Bols NC (2013) Development of a walleye cell line and use to study the effects of temperature on infection by viral hemorrhagic septicaemia virus (VHSV) group IVb. J Fish Dis (Accepted manuscript JFD-2013-179 – Online November 21, 2013)
  4. Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MTD, Eggen RIL, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee LEJ, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ (2013) A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Reg Tox Pharmacol 67: 506-530
  5. Dayeh VR, Bols NC, Tanneberger K, Schirmer K, Lee LEJ (2013) The use of fish derived cell lines for investigation of environmental contaminants – An Update following OECD’s fish toxicity testing framework n• 171. Current Protocols in Toxicology 56: 1.5.1 – 1.5.20
  6. Sansom B, Vo NTK, Kavanagh R, Hanner R, MacKinnon M, Dixon DG, Lee LEJ (2013) Rapid Assessment of the toxicity of oil sands process-affected waters using fish cell lines. In Vitro Cell. Dev. Biol.-Animal 49: 52-65

Published Abstracts since Dr Lee joined UFV:

  1. Trento MVC, Alexander JA, Rojas F, Chun A, Lee LEJ (2013) Rapid Assessment of the Genotoxic Potential of Environmental Contaminants Using Fish Cell Lines. 40th ATW Moncton (Accepted- to be presented October 2013)
  2. Vo NTK, Mak SMA, Lee LEJ, Lumsden JS, Dixon B, Bols NC (2013) Establishment of fibroblast cell lines from the skin and caudal fin of walleye, Sander vitreus, that are capable of forming extracellular collagen type 1 matrix. 2013 In Vitro Biology Meeting. Providence, RI. In Vitro Cell Dev. Biology-Animal 49: S45
  3. Gignac SJ, Vo NTK, MacLatchy DL, Lee LEJ (2013) Characterization and applications of Fundulus heteroclitus embryonic cell lines to ecotoxicology and fish health. 2013 In Vitro Biology Meeting. Providence, RI. In Vitro Cell Dev. Biology-Animal 49: S45
  4. Vo NTK, Bandukwala HA, Bender AW, Lumsden JS, Lee LEJ, Dixon B, Bols NC (2013) The susceptibility of walleye cell lines from the spleen stroma and caudal fin to viral hemorrhagic septicemia virus (VHSV). 2013 In Vitro Biology Meeting. Providence, RI. In Vitro Cell Dev. Biology-Animal 49: S30
  5. Ammendolia DA, Vo NTK, Server L, Lee LEJ, Dixon B, Bols NC (2013) Studying phagocytic activity of a rainbow trout monocyte/macrophage cell line. 52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  6. Bloch SR, Walsh SK, Chen CC, Vo NTK, Lee LEJ, Hodson PV, Bols NC (2013) Characterization of a multipotent cell line from the brain of the American eel (Anguilla rostrata). 52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  7. Gignac SJ, Vo NTK, MacLatchy DL, Lee LEJ (2013) Characterization of a continuous cell line from Fundulus heteroclitus, KFE-1, with neuroepithelial cell traits.52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  8. Schleicher KL, Vo NTK, Ammendolia DA, Van DB, Lee LEJ, Bols NC (2013) Establishment of an epithelial cell line from long-term primary cultures of ovarian fluids of rainbow trout, Oncorhynchus mykiss, 52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  9. Spiteri K, Vo NTK, Mikhaeil M, Way C, Lee LEJ (2013) Establishment and characterization of a continuous fibroblastic cell line from yellow perch (Perca flavescens), and it’s toxicological applications. 52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  10. Vo NTK, Lumsden JS, Dixon B, Lee LEJ, Bols NC (2013) Responses of double-stranded RNA (dsRNA) in cultured cells from walleye, Sander vitreus and other teleosts,52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  11. Vo NTK, Ammendolia DA, Kerimova A, Lee LEJ, Lumsden JS, Dixon B, Bols NC (2013) Cortisol delays the reproductive cycle of viral hemorrhagic septicemia virus IVb in walleye skin fibroblasts. 52nd Annual Meeting of the Canadian Society of Zoologists, Guelph, ON, May 13-17, 2013
  12. Spiteri K, Vo NTK, Mikhaeil M, Way C, Lee LEJ (2012) Toxicological Applications of a Yellow Perch (Perca flavescens) Cell Line.  39th Aquatic Toxicity Workshop, Sun Peaks, BC, Sep 30 - Oct 3, 2012, ***Winner Best Poster Award***

Additional Research Publications

Lucy Lee Research Publications 2001 to 2012

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